T-Cell Immunophenotyping Distinguishes Active From Latent Tuberculosis

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T-Cell Immunophenotyping Distinguishes Active From Latent Tuberculosis

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Deregulated microRNAs in CD4+ T cells from individuals with latent tuberculosis versus active tuberculosis

The mechanisms of latent tuberculosis (TB) infection remain elusive. Roles of microRNA (miRNA) have been highlighted in pathogen-host interactions recently. To identify miRNAs involved in the immune response to TB, expression profiles of miRNAs in CD4(+) T cells from patients with latent TB, active TB and healthy controls were investigated by microarray assay and validated by RT-qPCR. Gene onto...

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Discriminating Active Tuberculosis from Latent Tuberculosis Infection by flow cytometric measurement of CD161-expressing T cells

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Mycobacterium tuberculosis-specific T-cell responses in latent infection and active disease

Abbreviations 1 1 Abbreviations This thesis uses the international one-letter amino acid code. ADC albumin, dextrose, catalase Ag85a/b Antigen85 a/b of M. tuberculosis Alexa# Alexa Fluor® # AmCyan Anemonia majano cyan fluorescent protein APC antigen presenting cell APC allophycoerythrin APC-Cy7 allophycoerythrinCychrome7 ATP adenosine tri-phosphate BAK BCG activated killer cells BAL bronchoalve...

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ژورنال

عنوان ژورنال: The Journal of Infectious Diseases

سال: 2013

ISSN: 1537-6613,0022-1899

DOI: 10.1093/infdis/jit265